Publications

  • Mitochondrial metabolism is a key determinant of chemotherapy sensitivity in Colorectal Cancer

    Deborah Y Moss, Connor Brown, Andrew Shaw, Christopher McCann, Nikita Lewis, Aaron Phillips, Sarah Gallagher, William J McDaid, Andrew Roe, Aisling Y Coughlan, Brenton Cavanagh, Callum Ormsby, Fiammetta Falcone, Rachel McCole, Scott Monteith, Emily Rogan, Matilda Downs, Sudhir B Malla, Alexandra J Emerson, Letitia Mohammed-Smith, Shaun Sharkey, Peter F Gallagher, Arindam Banerjee, Sufyan Pandor, Brett Greer, Christopher Elliott, Aideen Ryan, Philip D Dunne, Vicky Coyle, Ian G Mills, Simon S McDade, Owen Sansom, Triona Ni Chonghaile, Daniel B Longley, Melissa J LaBonte, Emma M Kerr

    Paper Here

  • WHO elements – A new category of selfish genetic elements at the borderline between homing elements and transposable elements

    Matthieu Osborne, Athaliah Fubara, Eoin Ó Cinnéide, Aisling Y Coughlan, Kenneth H Wolfe

    Paper Here

  • Steroid-free combination of 5-azacytidine and venetoclax for the treatment of multiple myeloma

    Lyndsey Flanagan, Aisling Y Coughlan, Nicola Cosgrove, Andrew Roe, Yu Wang, Stephanie Gilmore, Izabela Drozdz, Claire Comerford, Jeremy Ryan, Emma Minihane, Salma Parvin, Michael O’Dwyer, John Quinn, Philip Murphy, Simon Furney, Siobhan Glavey, Tríona Ní Chonghaile

    PAPER Here

  • The Transcriptional Regulator Prdm1 Is Essential for the Early Development of the Sensory Whisker Follicle and Is Linked to the Beta-Catenin First Dermal Signal

    Pierluigi G Manti, Fabrice Darbellay, Marion Leleu, Aisling Y Coughlan, Bernard Moret, Julien Cuennet, Frederic Droux, Magali Stoudmann, Gian-Filippo Mancini, Agnès Hautier, Jessica Sordet-Dessimoz, Stephane D Vincent, Giuseppe Testa, Giulio Cossu, Yann Barrandon

    Paper here

  • Exploiting epigenetic dependencies in ovarian cancer therapy

    AY Coughlan, G Testa

    Paper here

  • Giant GAL gene clusters for the melibiose‐galactose pathway in Torulaspora

    A Venkatesh, AL Murray, AY Coughlan, KH Wolfe

    Paper here

  • Polymorphic centromere locations in the pathogenic yeast Candida parapsilosis

    M Ola, CE O'Brien, AY Coughlan, Q Ma, PD Donovan, KH Wolfe, G Butler

    Paper here

  • The yeast mating-type switching endonuclease HO is a domesticated member of an unorthodox homing genetic element family

    Aisling Y Coughlan, Lisa Lombardi, Stephanie Braun-Galleani, Alexandre AR Martos, Virginie Galeote, Frédéric Bigey, Sylvie Dequin, Kevin P Byrne, Kenneth H Wolfe

    Paper here

  • Genomic diversity and meiotic recombination among isolates of the biotech yeast Komagataella phaffii (Pichia pastoris)

    S Braun-Galleani, JA Dias, AY Coughlan, AP Ryan, KP Byrne, KH Wolfe

    Paper here

  • The reported point centromeres of Scheffersomyces stipitis are retrotransposon long terminal repeats

    AY Coughlan, KH Wolfe

    Paper here

  • Coverage-Versus-Length Plots, a Simple Quality Control Step for de Novo Yeast Genome Sequence Assemblies

    Alexander P Douglass, Caoimhe E O’Brien, Benjamin Offei, Aisling Y Coughlan, Raúl A Ortiz-Merino, Geraldine Butler, Kevin P Byrne, Kenneth H Wolfe

    Paper here

  • Population genomics shows no distinction between pathogenic Candida krusei and environmental Pichia kudriavzevii: One species, four names

    Alexander P Douglass, Benjamin Offei, Stephanie Braun-Galleani, Aisling Y Coughlan, Alexandre AR Martos, Raul A Ortiz-Merino, Kevin P Byrne, Kenneth H Wolfe

    Paper here

  • TPP riboswitch-dependent regulation of an ancient thiamin transporter in Candida

    Paul D Donovan, Linda M Holland, Lisa Lombardi, Aisling Y Coughlan, Desmond G Higgins, Kenneth H Wolfe, Geraldine Butler

    paper here

  • Evolutionary instability of CUG-Leu in the genetic code of budding yeasts

    Tadeusz Krassowski, Aisling Y Coughlan, Xing-Xing Shen, Xiaofan Zhou, Jacek Kominek, Dana A Opulente, Robert Riley, Igor V Grigoriev, Nikunj Maheshwari, Denis C Shields, Cletus P Kurtzman, Chris Todd Hittinger, Antonis Rokas, Kenneth H Wolfe

    paper here

  • Ploidy Variation in Kluyveromyces marxianus Separates Dairy and Non-dairy Isolates

    Raúl A Ortiz-Merino, Javier A Varela, Aisling Y Coughlan, Hisashi Hoshida, Wendel B Da Silveira, Caroline Wilde, Niels GA Kuijpers, Jan-Maarten Geertman, Kenneth H Wolfe, John P Morrissey

    paper here

  • Comparative genomics of biotechnologically important yeasts

    Robert Riley, Sajeet Haridas, Kenneth H Wolfe, Mariana R Lopes, Chris Todd Hittinger, Markus Göker, Asaf A Salamov, Jennifer H Wisecaver, Tanya M Long, Christopher H Calvey, Andrea L Aerts, Kerrie W Barry, Cindy Choi, Alicia Clum, Aisling Y Coughlan, Shweta Deshpande, Alexander P Douglass, Sara J Hanson, Hans-Peter Klenk, Kurt M LaButti, Alla Lapidus, Erika A Lindquist, Anna M Lipzen, Jan P Meier-Kolthoff, Robin A Ohm, Robert P Otillar, Jasmyn L Pangilinan, Yi Peng, Antonis Rokas, Carlos A Rosa, Carmen Scheuner, Andriy A Sibirny, Jason C Slot, J Benjamin Stielow, Hui Sun, Cletus P Kurtzman, Meredith Blackwell, Igor V Grigoriev, Thomas W Jeffries

    paper here

  • Centromeres of the Yeast Komagataella phaffii (Pichia pastoris) Have a Simple Inverted-Repeat Structure

    Aisling Y Coughlan, Sara J Hanson, Kevin P Byrne, Kenneth H Wolfe

    paper here
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